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Indian J Pediatr ; 2005 Oct; 72(10): 869-72
Article in English | IMSEAR | ID: sea-78634

ABSTRACT

Motor function abnormalities are a key feature of cerebral palsy. Spasticity is one of the main motor abnormalities seen in children with cerebral palsy. Spasticity is a velocity dependent increased resistance to movement. While in some children, spasticity may adversely impact the motor abilities, in others, it may help maintain posture and ability to ambulate. Thus, treatment to reduce spasticity requires careful consideration of various factors. Non-pharmacologic interventions used to reduce spasticity include physiotherapy, occupational therapy, use of adaptive equipment, various orthopedic surgical procedures and neurosurgical procedures. Pharmacologic interventions used for reducing spasticity in children with cerebral palsy reviewed in this article include oral administration of baclofen, diazepam, dantrolene and tizanidine, intrathecal baclofen, and local injections of botulinum toxin, phenol, and alcohol.


Subject(s)
Administration, Oral , Adrenergic alpha-Agonists/administration & dosage , Age Factors , Anti-Infective Agents, Local/administration & dosage , Baclofen/administration & dosage , Botulinum Toxins/administration & dosage , Cerebral Palsy/drug therapy , Child , Child, Preschool , Clonidine/administration & dosage , Dantrolene/administration & dosage , Diazepam/administration & dosage , Ethanol/administration & dosage , Humans , Infant , Injections, Intramuscular , Injections, Spinal , Muscle Relaxants, Central/administration & dosage , Muscle Spasticity/drug therapy , Neuromuscular Agents/administration & dosage , Phenol/administration & dosage , Time Factors
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